Thermo Fisher Scientific SCP2 Polyclonal Antibody, MaxPab

Applications

Tested Application

• Western Blot (WB): 1–5 µg/mL

Product Specifications

Product Specific Information

Protein Sequence:
MSSSPWEPAT LRRVFVVGVG MTKFVKPGAE NSRDYPDLAE EAGKKALADA QIPYSAVDQA CVGYVFGVAE CVLALGFEKM SKGSLGIKFS DRTIPTDKHV DLLINKYGLS AHPVAPQMFG YAGKEHMEKY GTKIEHFAKI GWKNHKHSVN NPYSQFQDEY SLDEVMASKE VFDFLTILQC CPTSDGAAAA ILASEAFVQK YGLQSKAVEI LAQEMMTDLP SSFEEKSIIK MVGFDMSKEA ARKCYEKSGL TPNDIDVIEL HDCFSTNELL TYEALGLCPE GQGATLVDRG DNTYGGKWVI NPSGGLISKG HPLGATGGHS CS

Target Information

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), resulting from transcription initiation from two independently regulated promoters.

• The proximal promoter initiates transcription of SCPx, a peroxisome-associated thiolase involved in oxidation of branched-chain fatty acids.
• The distal promoter initiates transcription of SCP2, an intracellular lipid transfer protein.

This gene is highly expressed in organs involved in lipid metabolism and may play a role in Zellweger syndrome, where peroxisomal deficiency impairs bile acid synthesis.
Alternative splicing produces multiple transcript variants encoding different isoforms.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.