Thermo Fisher Scientific LAP1 Monoclonal Antibody (RL13)
LAP1 단백질(A, B, C isoforms)을 인식하는 Thermo Fisher Monoclonal Antibody (RL13). Western blot, IHC, ICC/IF, IP에 적합하며, 사람·마우스·랫 시료에서 반응. Protein G 정제, 1 mg/mL 농도, PBS buffer에 0.05% sodium azide 포함.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | View 1 publication |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | RL13 |
| Immunogen | Pore complex-lamina fraction isolated from rat liver nuclear envelopes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2056886 |
Product Specific Information
MA1-074 detects lamin associated polypeptide (LAP) 1A, 1B, and 1C from rat, human, and mouse samples. This antibody does not cross-react with LAP 2.
MA1-074 has been successfully used in Western blot, immunofluorescence, immunohistochemistry, and immunoprecipitation procedures.
By Western blot, this antibody detects three distinct proteins of molecular weights approximately 65, 56, and 51 kDa representing LAP 1A, 1B, and 1C, respectively, in rat liver nuclear envelope fractions.
Immunofluorescence staining of LAP 1 in rat liver with MA1-074 results in exclusive labeling of the nuclear periphery and exhibits co-localization with lamin staining.
The MA1-074 immunogen is a pore complex-lamina fraction isolated from rat liver nuclear envelopes.
Target Information
Exopeptidase which selectively removes arginine and/or lysine residues from the N-terminus of several peptide substrates including Arg(0)-Leu-enkephalin, Arg(0)-Met-enkephalin, and Arg(-1)-Lys(0)-somatostatin-14.
Can hydrolyze leukotriene A4 (LTA-4) into leukotriene B4 (LTB-4).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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