Thermo Fisher Scientific CHRNB1 Monoclonal Antibody (B3)
인간 아세틸콜린 수용체 베타 소단위체를 인식하는 Mouse monoclonal antibody (Clone B3). Western blot, IHC, Flow cytometry, IP에 사용 가능. 높은 친화도와 특이적 결합력 보유. 연구용으로만 사용.
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Thermo Fisher Scientific CHRNB1 Monoclonal Antibody (B3)
Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:100–1:1,000 | |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | |
| Flow Cytometry (Flow) | Assay-dependent | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | B3 |
| Immunogen | Human Acetylcholine Receptor (AChR) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C or -20°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2745115 |
Product Specific Information
Mouse anti-Human Acetylcholine Receptor beta antibody, clone B3, exhibits homogenous, high-avidity binding to the beta subunit of nicotinic AChR. This receptor is an integral membrane cholinergic receptor composed of four additional subunits: alpha, delta, gamma (immature muscle), and epsilon (mature muscle).
Target Information
The muscle acetylcholine receptor comprises five subunits: two alpha, one beta, one gamma, and one delta. The CHRNB1 gene encodes the beta subunit. Upon acetylcholine binding, the receptor undergoes conformational change, opening an ion-conducting channel across the plasma membrane. Mutations in CHRNB1 are linked to slow-channel congenital myasthenic syndrome.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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