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Thermo Fisher Scientific WFS1 Polyclonal Antibody
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WFS1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, ER 항상성 연구 및 Wolfram 증후군 관련 연구에 활용 가능합니다. 농도 1 mg/mL, -20°C 보관.
- 판매단위
- pk
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627,600원VAT 포함 690,360원
Thermo Fisher Scientific · Thermo Fisher Scientific WFS1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human WFS1 (Accession O76024), corresponding to amino acid residues K193–A243 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851867 |
Product Specific Information
This antibody detects endogenous levels of total WFS1.
Target Information
WFS1 is a novel component of Wolfram syndrome, a rare form of juvenile diabetes. It plays an important role in maintaining endoplasmic reticulum (ER) homeostasis in the pancreas. WFS1 is normally up-regulated during insulin secretion, whereas inactivation of the protein can cause ER stress. Chronic ER stress is a major factor in Wolfram syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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