Thermo Fisher Scientific MPP1 Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

Positive test controls include: 293T, Mouse kidney, Mouse thymus.
The target is usually found in the following locations: Cell projection, Lipid-anchor, Membrane, Stereocilium.

Immunogen sequence:
MTLKASEGES GGSMHTALSD LYLEHLLQKR SRPEAVSHPL NTVTEDMYTN GSPAPGSPAQ VKGQEVRKVR LIQFEKVTEE PMGITLKLNE KQSCTVARIL HGGMIHRQGS LHVGDEILEI NGTNVTNHSV DQLQKAMKET KGMISLKVIP NQQSRLPALQ MFMRAQFDYD PKKDNLIPCK EAGLKFATGD IIQIINKDDS NWWQGRVEGS SKESAGLIPS PELQEWRVAS MAQSAPSEAP SCSPFGKKKK YKDKYLAKHS SIFDQLDVVS

Target Information

This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions.
The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain.
This gene product interacts with various cytoskeletal and cell junctional proteins in different tissues and cell types, and may be involved in regulating cell shape, hair cell development, neural patterning of the retina, and tumor suppression pathways in non-erythroid cells.
Multiple transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.