Thermo Fisher Scientific CAD Monoclonal Antibody (OTI10A3), TrueMAB
CAD 단백질을 인식하는 Mouse monoclonal 항체(OTI10A3)로 Western blot에 적합. Human 시료 반응성. 고순도 Affinity chromatography 정제. 안정한 PBS/BSA/glycerol buffer로 장기 보관 가능.
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Applications
- Western Blot (WB): 1:250–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10A3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1918–2225 of human CAD produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein associated with the enzymatic activities of the first three enzymes in the six-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, indicating a direct link between MAPK activation and de novo pyrimidine nucleotide biosynthesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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