Thermo Fisher Scientific IL21R Monoclonal Antibody (1C3B12)
IL21R 단백질을 표적으로 하는 마우스 단클론 항체로, Western Blot, Flow Cytometry, ELISA에 적합합니다. 고순도 Protein G 정제, PBS 버퍼에 0.05% sodium azide 포함. IL21 수용체 신호전달 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C3B12 |
| Immunogen | Purified recombinant fragment of human CD360 (AA: extra 20–232) expressed in HEK293-6e cells supernatant |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090860 |
Target Information
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors and forms a heterodimeric receptor complex with the common gamma-chain, which is also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth-promoting signal of IL21 and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. Ligand binding activates downstream signaling molecules including JAK1, JAK3, STAT1, and STAT3. Knockout studies in mice suggest a role in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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