Thermo Fisher Scientific IL21R Monoclonal Antibody (1C3G9)
IL21R 단백질을 인식하는 마우스 모노클로날 항체. Western blot, ICC/IF, Flow cytometry, ELISA에 적합. 인간 시료 반응성. Protein G 정제, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:25–1:200 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C3G9 |
| Immunogen | Purified recombinant fragment of human CD360 (AA: extra 20–232) expressed in HEK293-6e cells supernatant |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090772 |
Target Information
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors and forms a heterodimeric receptor complex with the common gamma-chain, which is also shared by receptors for IL2 and IL5. This receptor transduces the growth-promoting signal of IL21 and plays a key role in the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. Ligand binding activates downstream signaling molecules including JAK1, JAK3, STAT1, and STAT3. Knockout studies in mice suggest a role in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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