
Thermo Fisher Scientific ENT1 Polyclonal Antibody
Rabbit polyclonal antibody specific to human ENT1. Validated for IHC (Paraffin) with high specificity. Supplied as a liquid, 1 mg/mL concentration, purified by antigen affinity chromatography. Suitable for research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 10–15 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from internal region of human ENT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550891 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Orangutan, Gibbon, Monkey: 100%
- Marmoset: 94%
- Horse: 81%
Target Information
This gene belongs to the equilibrative nucleoside transporter (ENT) family. It encodes a transmembrane glycoprotein localized to the plasma and mitochondrial membranes, mediating cellular uptake of nucleosides. The transporter is sensitive to inhibition by nitrobenzylthioinosine. Nucleoside transporters are essential for nucleotide synthesis in cells lacking de novo nucleoside synthesis pathways and for uptake of cytotoxic nucleosides used in cancer and antiviral therapies. Multiple alternatively spliced variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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