Thermo Fisher Scientific CD249 (BP-1) Monoclonal Antibody (6C3), FITC, eBioscience

Applications and Tested Dilution

• Application: Flow Cytometry (Flow)
• Tested Dilution: 1 µg/test
• Publications: 6 publications available (see references)

Product Specifications

Available Formats

• Unconjugated
• APC
• Biotin
• PE
• PerCP-eFluor 710
• Custom conjugation available upon request

Product Specific Information

The 6C3 monoclonal antibody reacts with mouse BP-1 (also known as Ly-51 and 6C3 antigen), a 140 kDa type II transmembrane protein forming a disulfide-linked homodimer. BP-1 exhibits aminopeptidase A (APA) enzymatic activity and is expressed on bone marrow stromal cells, thymic cortical epithelial cells, and pre-B cells during early B cell development. Expression on pre-B cells can be upregulated by IL-7.

Applications Reported: Flow cytometric analysis
Applications Tested: Tested on mouse bone marrow cells at ≤1 µg/test. A test is defined as the amount of antibody that stains cells in a 100 µL final volume. Optimal titration is recommended.

Fluorescence Properties:

• Excitation: 488 nm
• Emission: 520 nm
• Laser: Blue Laser

Filtration: 0.2 µm post-manufacturing filtered

Target Information

CD249 (BP-1) is involved in the catabolic pathway of the renin-angiotensin system and may regulate growth and differentiation of early B-lineage cells.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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