Thermo Fisher Scientific Phospho-HDAC2 (Ser394) Polyclonal Antibody
HDAC2 단백질의 Ser394 인산화 부위를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot 및 ICC/IF에 적합하며, 인간, 마우스, 랫트 시료에 반응. 고순도 정제 및 안정적 PBS/glycerol buffer로 장기 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HDAC2 (Accession Q92769), corresponding to amino acid residues around phosphorylated Ser394. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816494 |
Product Specific Information
This antibody detects endogenous levels of HDAC2 only when phosphorylated at Serine 394.
Target Information
HDAC2 belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3, and H4).
This protein forms transcriptional repressor complexes by associating with various proteins, including YY1, a mammalian zinc-finger transcription factor.
It plays an important role in transcriptional regulation, cell cycle progression, and developmental events.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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