Thermo Fisher Scientific RPS6 Polyclonal Antibody
RPS6 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, IP 등에 사용 가능. 인간 및 생쥐 반응성, 항원 친화 크로마토그래피로 정제. 액상 형태, 4°C 보관. 연구용으로 세포 성장 및 단백질 합성 연구에 적합.
- 판매단위
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 200 and the C-terminus (residue 249) of Human Ribosomal Protein S6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, predicted to react with Rat, X. laevis, Chicken, and Bovine
Target Information
Ribosomes are organelles that catalyze protein synthesis and consist of a small 40S subunit and a large 60S subunit, composed of 4 RNA species and about 80 distinct proteins.
This gene encodes a cytoplasmic ribosomal protein that is part of the 40S subunit and belongs to the S6E family. It is a major substrate of ribosomal protein kinases, with phosphorylation of five C-terminal serine residues by different kinases.
Phosphorylation is induced by various stimuli such as growth factors, tumor-promoting agents, and mitogens, while dephosphorylation occurs during growth arrest.
The protein may regulate cell growth and proliferation via selective translation of specific mRNA classes.
Multiple processed pseudogenes of this gene are dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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