Thermo Fisher Scientific RPS6 Polyclonal Antibody
Rabbit polyclonal antibody against human RPS6 protein for WB, IHC, and IP applications. Recognizes C-terminal region (residues 200–249). Suitable for multiple species. Supplied as liquid, unconjugated form, 0.2 mg/mL concentration, stored at 4°C.
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- A300557Ax (2개 옵션)
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 200 and the C-terminus (residue 249) of Human Ribosomal Protein S6 (UniProt ID: P62753-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Predicted to react with Rat, X. laevis, Chicken, and Bovine based on 100% sequence identity
Target Information
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit, composed of 4 RNA species and ~80 distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is part of the 40S subunit and belongs to the S6E family. It serves as a major substrate for ribosomal protein kinases, with phosphorylation of five C-terminal serine residues mediated by various kinases. Phosphorylation is induced by growth factors, tumor-promoting agents, and mitogens, while dephosphorylation occurs during growth arrest. The protein may regulate cell growth and proliferation via selective translation of specific mRNA classes. Multiple processed pseudogenes are distributed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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