Thermo Fisher Scientific Perilipin 1 Polyclonal Antibody
Perilipin 1 단백질을 표적하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC, Flow Cytometry 등에 사용 가능. 다양한 종(Fish, Human, Mouse, Pig, Rat)에 반응하며 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | View 1 publication |
| Flow Cytometry (Flow) | 5–10 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fish, Human, Mouse, Pig, Rat |
| Published Species | Bovine, Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 450–522 (C-terminus) of human Perilipin protein (Swiss-Prot# O60240) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718775 |
Target Information
Adipose tissue serves as an energy reserve and is tightly regulated in animals. Adipocytes produce several physiologically important proteins such as lipoprotein lipase (LPL), leptin, Acrp30, resistin, and perilipin.
Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated and localized to the surface of lipid droplets. Upon lipolytic stimulation, perilipin is phosphorylated by protein kinase A and modulates hormone-sensitive lipase (HSL) activity, influencing triacylglycerol hydrolysis.
Perilipin expression is restricted to adipocytes and steroidogenic cells, with two known isoforms (A and B) arising from differential splicing of a single gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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