Thermo Fisher Scientific BTB1 Polyclonal Antibody
BTB1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, ELISA, IP에 적합합니다. 인간 단백질에 반응하며, 액상 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제 및 안정한 보관 조건을 제공합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 – 1:2,000 |
| ELISA | 1:5,000 – 1:25,000 |
| Immunoprecipitation (IP) | 1:500 – 1:3,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Affinity purified antibody prepared from whole rabbit serum immunized with a synthetic peptide corresponding to an internal region of Human Btb1 (ankyrin repeat protein BAA92655, suggested to bind CUL3). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.63 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
Target Information
The protein encoded by this gene binds to Bruton’s tyrosine kinase (BTK) and downregulates BTK’s kinase activity. It also disrupts BTK-mediated calcium mobilization and negatively regulates NF-κB-driven transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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