Thermo Fisher Scientific CD9 Polyclonal Antibody
CD9 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P)에서 검증됨. 세포막 단백질 CD9 연구용으로 적합하며, 항원 친화 크로마토그래피로 정제됨. 연구용 시약으로 진단용 사용 불가.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encoding the full length of human CD9 (UniProt ID: P21926-1, Antigen Range: 1–228) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Tonsil
- Cellular location: Cell membrane
Target Information
CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, and by neurons and glial cells in the peripheral nervous system.
CD9 belongs to the tetraspanin family, which spans the membrane four times. In pre-B cells and platelets, CD9 regulates cell activation and aggregation through association with integrin CD41/CD61 (GPIIb/GPIIIa).
It is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion. CD9 plays roles in cell attachment, proliferation, and MHC II molecule association on dendritic cells for effective T cell stimulation.
CD9 expression is critical in differentiation, adhesion, signal transduction, and suppression of cancer cell motility and metastasis. It is considered a metastasis suppressor in solid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(500-11014_CD9_P21926-1_Rabbit.svg, 500-11014_CD9_P21926-1_Rabbit_PDP.jpeg)
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