Thermo Fisher Scientific SHP2 Polyclonal Antibody
SHP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, 항원 친화 크로마토그래피로 정제됨. 인간, 마우스, 랫트 반응성. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 14 amino acid peptide from near the amino terminus of human SHP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152488 |
Product Specific Information
- Suggested positive control: Mouse skeletal muscle tissue lysate
- PA5-20279 can be used with blocking peptide PEP-0409
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs regulate various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains two tandem Src homology-2 domains that mediate interaction with substrates. It is widely expressed in most tissues and plays a regulatory role in diverse signaling events including mitogenic activation, metabolic control, transcription regulation, and cell migration.
Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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