Thermo Fisher Scientific Granzyme B Monoclonal Antibody (351927), PerCP
인간 Granzyme B를 인식하는 Mouse IgG2a 단클론 항체로 PerCP 형광 접합체 형태 제공. Flow cytometry에 적합하며 교차 반응성이 낮음. 단백질 A/G 정제, BSA 포함 완충액에 보관. 4°C에서 암소 저장, 동결 금지.
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Applications
- Flow Cytometry (Flow): 10 µL per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 351927 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Granzyme B (Gly19–Tyr247) |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | Buffered saline solution with BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609542 |
Additional Formats
Product Specific Information
This antibody does not cross-react with recombinant human Granzyme A, Granzyme H, recombinant mouse Granzyme B, Granzyme C, Granzyme D, or Granzyme G.
Target Information
Granzyme B is a member of the granzyme serine protease family found in cytotoxic T cells and NK cell granules. It plays a crucial role in inducing apoptosis in target cells by activating caspase cascades and mitochondrial pathways. Granzyme B interacts with mannose 6-phosphate receptor, functioning as a death receptor during cytotoxic T cell-mediated apoptosis. It is expressed only in activated cytotoxic lymphocytes and not in non-cytotoxic lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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