Thermo Fisher Scientific LIN28A Monoclonal Antibody (14E6-4E6), DyLight 488
LIN28A 단백질 검출용 DyLight 488 형광 표지 단일클론 항체. 인간 및 생쥐 시료에서 ICC/IF 및 유세포분석(Flow Cytometry)에 적합. 단백질 A로 정제된 고순도 항체로, iPSC 연구 및 발달 생물학 연구에 활용 가능.
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Thermo Fisher Scientific LIN28A Monoclonal Antibody (14E6-4E6), DyLight 488
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:50–1:500 |
| Flow Cytometry (Flow) | 1:50–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 14E6-4E6 |
| Immunogen | Full-length human recombinant LIN28A protein expressed in bacteria |
| Conjugate | DyLight™ 488 |
| Excitation / Emission Max | 492 / 519 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536673 |
Additional Formats
Product Specific Information
MA1-016-D488 has been successfully used in ICC/IF and flow cytometry applications on human and mouse samples.
It can be used for immunofluorescence analysis of LIN28 in human induced pluripotent stem cells (iPSCs).
Target Information
Lin28 is a transcription factor originally identified for its role in developmental timing in C. elegans.
Its involvement in development makes it valuable for creating stem cells that may aid in regenerative therapies for degenerative diseases.
Induced pluripotent stem (iPS) cells can be generated by expressing Lin28 along with transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts.
Recent studies show iPS cells can also be created using plasmid expression of Lin28, Sox2, POU5F1, and c-Myc—avoiding viral introduction and improving safety for regenerative medicine applications.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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