Thermo Fisher Scientific SOX2 Monoclonal Antibody (20G5), HRP

Applications

Western Blot (WB)

• Tested Dilution: 1:250–1:1,000
• Publications: View 2 publications

Product Specifications

Available Formats

• Unconjugated
• DyLight 488
• DyLight 550
• DyLight 650
• Request custom conjugation

Product Specific Information

MA1-014-HRP has been successfully used in Western blot with human and mouse samples.
Western blot analysis of MA1-014-HRP specifically detects SOX2 protein at ~36 kDa in the nucleus of embryonal carcinoma cells.

Target Information

SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate.
The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system and also regulates gene expression in the stomach.
The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins.
Mutations in the SOX2 gene have been associated with bilateral anophthalmia, optic nerve hypoplasia, and syndromic microphthalmia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.