Thermo Fisher Scientific nNos Polyclonal Antibody
nNOS 단백질을 인식하는 Rabbit Polyclonal Antibody로 WB, IHC, ICC, ELISA 등 다양한 응용에 적합함. Human, Mouse, Rat 반응성 보유. KLH 결합 합성 펩타이드(aa 51-150)로 면역원 제작. 고순도 Protein A 정제 및 1 mg/mL 농도. 연구용으로만 사용 가능.
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Thermo Fisher Scientific nNos Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human NOS-1, amino acids 51–150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH, and O₂) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin, and heme).
Several distinct NOS isoforms have been described and represent the products of three distinct genes. These include two constitutive Ca²⁺/CaM-dependent forms of NOS:
- NOS1 (ncNOS): Activity first identified in neurons
- NOS3 (ecNOS): Activity first identified in endothelial cells
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: BS-0156R_nNOS_P29475-1_Rabbit.svg, BS-0156R_nNOS_P29475-1_Rabbit_PDP.jpeg)
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