Thermo Fisher Scientific SRC1 Polyclonal Antibody
SRC-1 단백질 검출용 Thermo Fisher Scientific 폴리클로날 항체. Western blot, IHC, ICC 등 다양한 응용에 적합. 인간, 생쥐, 조류 등에서 반응. 항원 친화 크로마토그래피로 정제된 고순도 제품. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | View 8 publications |
| Immunohistochemistry (IHC) | - | View 4 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | 1 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL | - |
| Immunoprecipitation (IP) | - | View 1 publication |
| ChIP assay (ChIP) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Avian, Human, Mouse |
| Published Species | Amphibian, Avian, Chicken, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues S(8) S D P A N P D S H K R K G S P C(24) of human SRC-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2251288 |
Product Specific Information
PA1-840 detects steroid receptor coactivator-1 (SRC-1) from human, mouse, and Japanese quail tissues and cells.
It has been successfully used in Western blot, immunocytochemistry, and immunohistochemistry procedures.
By Western blot, this antibody detects an ~165 kDa protein representing SRC-1 and a smaller, unknown protein at ~40 kDa from HeLa cell lysate.
Immunocytochemical staining of SRC-1 in HeLa cells with PA1-840 results in nuclear staining.
The PA1-840 immunogen is a synthetic peptide corresponding to residues S(8) S D P A N P D S H K R K G S P C(24) of human SRC-1.
This immunizing peptide (Cat. # PEP-044) is available for use in neutralization and control experiments.
Target Information
Clone 1135 recognizes SRC-1, steroid-receptor coactivator-1.
SRC-1 is a member of a gene family that functions in the full transcriptional activation of the steroid hormone receptor superfamily and contains intrinsic histone acetyltransferase activity.
SRC-1 has a molecular weight of 160 kDa and possesses a basic helix-loop-helix (bHLH)-PAS domain.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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