Thermo Fisher Scientific PDE1B Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 190-536 of human PDE1B (NP_000915.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PDE1B,uniProtId:Q01064-1,ncbiNodeId:9606,antigenRange:190-536,antigenLength:536,antigenImageFileName:PA5-110086_PDE1B_Q01064-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110086_PDE1B_Q01064-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.47 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855497

Product Specific Information

Immunogen sequence: RHNLISRFKI PTVFLMSFLD ALETGYGKYK NPYHNQIHAA DVTQTVHCFL LRTGMVHCLS EIELLAIIFA AAIHDYEHTG TTNSFHIQTK SECAIVYNDR SVLENHHISS VFRLMQDDEM NIFINLTKDE FVELRALVIE MVLATDMSCH FQQVKTMKTA LQQLERIDKP KALSLLLHAA DISHPTKQWL VHSRWTKALM EEFFRQGDKE AELGLPFSPL CDRTSTLVAQ SQIGFIDFIV EPTFSVLTDV AEKSVQPLAD EDSKSKNQPS FQWRQPSLDV EVGDPNPDVV SFRSTWVKRI QENKQKWKER AASGITNQMS IDELSPCEEE APPSPAEDEH NQNGNLD

Target Information

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.