Thermo Fisher Scientific DLL4 Monoclonal Antibody (15)
인간 DLL4 단백질을 인식하는 Mouse IgG2a 단클론 항체로 ELISA에 적합합니다. 보존제가 없으며 필요 시 sodium azide를 추가 권장합니다. 혈관 발달 및 종양 연구용으로 활용됩니다. 단기 4°C, 장기 -20°C 보관.
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Thermo Fisher Scientific DLL4 Monoclonal Antibody (Clone 15)
Applications
- ELISA (ELISA)
Tested Dilution: 1:1,000–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 15 |
| Immunogen | Recombinant Human DLL4/Delta-like 4 protein (Met1–Pro524) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786083 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human DLL4/Delta-like 4.
Target Information
Delta-like ligand 4 (DLL4), also known as Delta-4, is a transmembrane ligand for the Notch1 receptor. DLL4 is expressed in the vasculature and plays a key role in vascular development. It is induced by VEGF as a negative feedback regulator to control angiogenic sprouting and promote formation of a differentiated vascular network. DLL4 is strongly expressed in tumor vessels of clear-cell renal tumors and bladder cancer. Inhibition of DLL4 increases vascular proliferation but impairs maturation, leading to reduced tumor growth without apparent toxicity.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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