Thermo Fisher Scientific mPR gamma Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal mPR gamma 항체로 Western blot에 적합. 1 mg/mL 농도의 액상 형태이며 항원 친화 크로마토그래피로 정제됨. 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용으로만 사용 가능.
- 카탈로그번호
- PA536352
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 281–330 of Human mPR gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2553487 |
Product Specific Information
- Detects endogenous protein at a molecular weight of 38 kDa.
- Purity is >95% by SDS-PAGE.
Target Information
The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel, membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways.
Three distinct groups, designated alpha, beta, and gamma, comprise this gene family. While all contain 7 transmembrane domains, they show distinct distributions in reproductive, neural, kidney, and intestinal tissues. These characteristics separate them from nuclear progestin receptors and imply similarity to G-protein coupled receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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