Thermo Fisher Scientific MRG15 Polyclonal Antibody
MRG15 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 고순도(>95%)이며 41 kDa 단백질을 검출합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 23–75 of human MRG15 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553491 |
Product Specific Information
- Detects endogenous MRG15 protein at approximately 41 kDa.
- Purity: >95% by SDS-PAGE.
Target Information
MRG15 is a component of the NuA4 histone acetyltransferase (HAT) complex involved in transcriptional activation of select genes, primarily through acetylation of nucleosomal histones H4 and H2A.
This modification may alter nucleosome–DNA interactions and promote association of modified histones with transcriptional regulators.
The complex is implicated in transcriptional programs related to oncogene and proto-oncogene mediated growth induction, tumor suppressor-mediated growth arrest, replicative senescence, apoptosis, and DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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