Thermo Fisher Scientific IKK alpha Monoclonal Antibody (3G12)
Human CHUK 단백질을 인식하는 IKK alpha 단클론 항체(3G12)로, WB와 ELISA에 사용 가능. Mouse IgG1 형식이며 비결합형 액상 제품. 단기 4°C, 장기 -20°C 보관. 연구용으로 NF-κB 신호전달 연구에 적합.
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- MA515691
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- pk
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Thermo Fisher Scientific IKK alpha Monoclonal Antibody (3G12)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G12 |
| Immunogen | Purified recombinant fragment of human CHUK expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% Sodium Azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10985543 |
Product Specific Information
MA5-15691 targets CHUK in indirect ELISA and WB applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of human CHUK expressed in E. coli.
MA5-15691 detects CHUK with a predicted molecular weight of approximately 85 kDa.
Target Information
CHUK (IKK alpha) is a serine/threonine kinase involved in signal transduction and cellular communication.
It is part of the cytokine-activated protein complex that inhibits the NF-κB complex.
IKK alpha, together with IKK beta and the regulatory protein NEMO (IKK gamma), phosphorylates IκB proteins, targeting them for ubiquitin-mediated degradation.
This kinase plays a key role in inflammation and cell survival processes.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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