Thermo Fisher Scientific AMID Polyclonal Antibody
Thermo Fisher Scientific의 AMID Polyclonal Antibody는 인간 PRG3 단백질을 검출하기 위한 고품질 항체로 Western blot에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific AMID Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution
- 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide: V(170) T L I H S Q V A L A D K E L L(185) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2169232 |
Product Specific Information
PA1-4345 detects the human PRG3 protein in human samples.
PA1-4345 has been successfully used in Western blot procedures.
By Western blot, this antibody detects a ~41 kDa protein representing PRG3 in human heart lysate.
The PA1-4345 immunizing peptide corresponds to amino acid residues 170–185 of the 41 kDa human PRG3 protein.
Target Information
The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses.
PRG3 (p53-responsive gene 3) is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells.
PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor (AIF).
Unlike AIF, PRG3 localizes in the cytoplasm and its ectopic expression induces apoptosis.
The PRG3 gene is thus a novel p53 target gene in a p53-dependent apoptosis pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA1-4345_AMID_Q9BRQ8-1_Rabbit.svg, PA1-4345_AMID_Q9BRQ8-1_Rabbit_PDP.jpeg)
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