Thermo Fisher Scientific CYSLTR1 Polyclonal Antibody
Rabbit polyclonal antibody against CYSLTR1 for Western blot applications. Recognizes amino acids 203–296 of CysLT1 receptor. Suitable for A431, H1299, HeLa cells. Supplied as liquid, 0.38 mg/mL, stored at 4°C short term or -20°C long term.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 203–296 of CysLT1 Receptor (Uniprot ID#Q9Y271) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.38 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2551987 |
Product Specific Information
- Recommended positive controls: A431, H1299, HeLa
- Predicted reactivity: Bovine (100%)
- Store as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least two receptors: the protein encoded by this gene (CYSLTR1) and CYSLTR2. This receptor belongs to the G protein-coupled receptor superfamily. Activation by LTD4 results in contraction and proliferation of smooth muscle, edema, eosinophil migration, and damage to the mucus layer in the lung.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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