
Thermo Fisher Scientific CCR8 Polyclonal Antibody
CCR8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human 시료에 반응합니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 4°C 또는 -20°C에서 안정적으로 보관 가능합니다.
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Thermo Fisher Scientific CCR8 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 255–355 of CCR8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2551985 |
Product Specific Information
- Recommended positive control: K562
- Store product as a concentrated solution.
- Centrifuge briefly before opening the vial.
Target Information
CCR8 encodes a member of the beta chemokine receptor family, predicted to be a seven-transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into inflammatory sites. This receptor protein preferentially expresses in the thymus.
I-309, thymus activation-regulated cytokine (TARC), and macrophage inflammatory protein-1 beta (MIP1 beta) are identified ligands of this receptor.
Studies suggest CCR8’s role in regulation of monocyte chemotaxis and thymic cell apoptosis, contributing to the proper positioning of activated T cells within antigenic challenge sites and specialized areas of lymphoid tissues.
CCR8 expression has been reported in spleen, thymus, natural-killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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