Thermo Fisher Scientific PKC mu Recombinant Rabbit Monoclonal Antibody (JM30-17)
PKC mu 단백질을 검출하기 위한 재조합 토끼 단클론 항체로, Western blot에 적합합니다. HEK293 세포에서 발현되며 높은 특이성과 일관성을 제공합니다. 단백질 A로 정제되었으며, 1 mg/mL 농도의 액상 형태로 공급됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JM30-17 |
| Immunogen | Synthetic peptide within Human PKC (aa 201–250) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% Sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2810020 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed, and the best clones are selected for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the extensive rabbit immune repertoire
Target Information
The PKC family of serine/threonine kinases, including PRKCN (PKD3), is activated via intracellular signal transduction pathways. In humans, at least 12 PKC isoforms have been identified, differing in structure, tissue distribution, localization, and substrate specificity.
PKC mu activation depends on phosphorylation at Ser744 and Ser748 through a PKC-dependent signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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