Thermo Fisher Scientific TWIST2 Monoclonal Antibody (OTI9F11), TrueMAB
TWIST2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 적합합니다. 인간 TWIST2 재조합 단백질을 면역원으로 제작되었으며, 동결건조 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제, -20°C 보관 권장.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9F11 |
| Immunogen | Full length human recombinant protein of human TWIST2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform desalting using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
TWIST2 binds to the E-box consensus sequence (5'-CANNTG-3') as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A, and MEF2C. It represses expression of proinflammatory cytokines (TNFA, IL1B) and is involved in postnatal glycogen storage and energy metabolism. TWIST2 inhibits premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by altering signal transduction responses to growth factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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