Thermo Fisher Scientific TWIST2 Monoclonal Antibody (OTI6G9), TrueMAB
TWIST2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 최적화됨. Human 시료에 반응하며, Lyophilized 형태로 제공. PBS buffer와 trehalose 포함, 보존제 무첨가. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6G9 |
| Immunogen | Full length human recombinant TWIST2 protein produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TWIST2 binds to the E-box consensus sequence (5’-CANNTG-3’) as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A, and MEF2C.
It represses proinflammatory cytokine expression (TNFA, IL1B), participates in glycogen storage and energy metabolism, and regulates osteoblast differentiation by modulating signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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