Thermo Fisher Scientific RPAP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to residues in human RPAP1

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2553968

Product Specific Information

This antibody detects endogenous protein at a molecular weight of 153 kDa.

Purity is >95% by SDS-PAGE.

Target Information

RNA polymerases transcribe nuclear genes for ribosomal RNA and are integral components of ribosomal biogenesis. RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA. RNA polymerase II (Pol II) synthesizes mRNA. RNA polymerase III (Pol III) transcribes class III genes, encoding a number of small ribosomal RNA molecules including tRNA and 5S rRNA. RPAP1 (RNA polymerase II associated protein 1) is a 1, 393 amino acid nuclear protein that is thought to connect Pol II to acetylated Histone H3 and regulators of protein complex formation. A member of the RPAP1 family, RPAP1 exists as three alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 15q15.1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.