Thermo Fisher Scientific RPAP1 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Product Specific Information

This antibody detects endogenous RPAP1 protein at a molecular weight of approximately 153 kDa.
Purity is >95% by SDS-PAGE.

Target Information

RNA polymerases transcribe nuclear genes for ribosomal RNA and are integral components of ribosomal biogenesis.

• RNA polymerase I (Pol I): Located in the nucleolus; transcribes class I genes coding for large ribosomal RNA.
• RNA polymerase II (Pol II): Synthesizes mRNA.
• RNA polymerase III (Pol III): Transcribes class III genes encoding small ribosomal RNA molecules including tRNA and 5S rRNA.

RPAP1 (RNA polymerase II associated protein 1) is a 1,393 amino acid nuclear protein thought to connect Pol II to acetylated Histone H3 and regulators of protein complex formation.
A member of the RPAP1 family, RPAP1 exists as three alternatively spliced isoforms encoded by a gene located on human chromosome 15q15.1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.