Thermo Fisher Scientific SCARA5 Polyclonal Antibody
SCARA5 단백질을 인식하는 Sheep Polyclonal 항체로, Western blot 및 유세포분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 트레할로스 완충액에 동결건조 형태로 제공됩니다. 마우스 시료에 반응하며, 보존제는 포함되어 있지 않습니다.
- 카탈로그번호
- PA548058
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CHO-derived recombinant mouse SCARA5 (Arg83–Pro491) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606759 |
Product Specific Information
- In direct ELISAs, less than 40% cross-reactivity with recombinant human SCARA5 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Scavenger receptor class A member 5 (SCARA5), also known as TESR, is part of the scavenger receptor superfamily, which includes multiple members with diverse structures and functions.
SCARA5 is a cell-surface receptor containing a collagen-like domain and an N-terminal scavenger receptor cysteine-rich domain typical of the class A subfamily.
Unlike other class A receptors, SCARA5 does not endocytose acetylated or oxidized low-density lipoprotein but binds serum ferritin and mediates its endocytosis, suggesting a role in non-transferrin iron delivery.
At least four isoforms of SCARB1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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