Thermo Fisher Scientific alpha Tubulin Chimeric Recombinant Mouse Monoclonal Antibody (F2C)
인간 알파튜불린에 특이적으로 결합하는 재조합 마우스 단클론 항체입니다. Western blot 및 ELISA에 사용 가능하며, HEK293 세포에서 발현된 IgG1 형식의 항체입니다. 단백질 A로 정제되었으며, PBS에 0.02% ProClin 300이 포함된 액상 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, lambda |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | F2C |
| Immunogen | Human MBP (microtubule-binding protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074389 |
Product Specific Information
- Specificity: Binds specifically to human alpha-tubulin (no crossreactivity with beta-tubulin).
Target Information
Alpha Tubulin is part of a heterodimer consisting of alpha and beta tubulin subunits. Each subunit is approximately 55 kDa, homologous but not identical. The alpha-beta tubulin heterodimer forms the basic building block of microtubules, which are cylindrical filamentous structures present in nearly all eukaryotic cells.
Microtubules serve as structural supports and intracellular transport lines, playing a key role in mitosis. They are composed mainly of alpha and beta tubulins, while gamma tubulin is essential for microtubule nucleation. Multiple alpha and beta tubulin genes exist and are highly conserved among species. The alpha tubulin gene shows high similarity to the mouse and rat Tuba1 gene, with expression predominantly found in morphologically differentiated neurologic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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