Thermo Fisher Scientific Heart Fatty Acid Binding Protein (H-FABP)/FABP3 Monoclonal Antibody (FABP3/3430)
인체 FABP3 단백질을 인식하는 마우스 단클론 항체로, IHC(P), IHC(PFA), Peptide Array 등에 사용 가능. 단백질 A/G로 정제된 액상 항체이며, 보존제 없이 PBS(pH 7.4)에 용해. 연구용으로 세포 내 지방산 결합 단백질 연구 및 손상 세포 마커 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FABP3/3430 |
| Immunogen | Human recombinant FABP3 protein fragment (aa 1–127) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Fatty acid binding proteins (FABP) are small (approximately 13–14 kDa) intracellular proteins with high tissue specificity. They bind long-chain fatty acids and play an important role in intracellular lipid transport and metabolism.
There are at least six distinct types of FABP, each showing unique tissue expression patterns. Due to their small size, FABPs can rapidly leak from damaged cells, leading to elevated serum levels.
Liver FABP serves as a sensitive marker for hepatocyte damage both in vitro and in vivo, and reduced FABP presence can help identify damaged tissue areas. Additionally, L-FABP is useful for detecting hepatocyte lysis in toxicology assays and monitoring liver injury during and after transplantation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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