Thermo Fisher Scientific RAC2 Polyclonal Antibody
RAC2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB와 IHC(P)에서 검증됨. Human 및 Mouse 반응성. 고순도 항원 친화 크로마토그래피 정제. 장기 보관 시 -20°C에서 안정적.
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Applications
- Western Blot (WB): 1:500–1:3,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–189 of Human RAC2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.43 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2547156 |
Product Specific Information
- Recommended positive controls: Molt-4, Raji
- Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (96%), Drosophila (92%), Xenopus laevis (96%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia, and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42, which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are essential components of NADPH oxidase, the enzyme responsible for generating free radicals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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