Thermo Fisher Scientific TNFR2 Monoclonal Antibody (MR2-1), FITC
인간 TNFR2에 특이적인 단클론 항체로 FITC 형광 표지되어 있습니다. WB, ICC/IF, Flow Cytometry 등 다양한 응용에 사용 가능하며, 단백질 G 정제 및 PBS/BSA 버퍼에 보관됩니다. 4°C 암소 상태에서 보관하며 연구용으로 적합합니다.
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Thermo Fisher Scientific TNFR2 Monoclonal Antibody (MR2-1), FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
| Immunoprecipitation (IP) | 1:50 |
| Functional Assay | 1:50 |
| Inhibition Assays (IA) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MR2-1 |
| Immunogen | sTNF-R75 purified from culture supernatant of NSO cells transfected with extracellular part of TNF-R75 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_3093259 |
Product Specific Information
This antibody reacts with the extracellular part of TNF-RII and also with the soluble receptor. It cross-reacts with rhesus and cynomolgus natural TNF-RII.
Target Information
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha and lower affinity for TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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