Thermo Fisher Scientific TREM1 Monoclonal Antibody (6B1)
인간 TREM-1 단백질을 인식하는 Mouse IgG1 단클론 항체로, 막결합형 및 가용형 TREM-1 모두에 반응합니다. Western blot, Flow cytometry, Functional assay에 사용 가능하며, TREM-1과 리간드 간 상호작용을 중화합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
| Functional Assay (Functional) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6B1 |
| Immunogen | Recombinant TREM-1 - IgG1 fusion protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_3091111 |
Product Specific Information
The monoclonal antibody 6B1 recognizes both membrane-bound and soluble TREM-1. It also neutralizes the interaction between TREM-1 and its ligand.
Target Information
TREM1 (Triggering Receptor Expressed on Myeloid Cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections. It stimulates the release of pro-inflammatory chemokines and cytokines and increases surface expression of cell activation markers. TREM1 and related proteins such as TREM2 are thought to modulate the inflammatory response. TREM1 has been linked to inflammatory bowel disease, resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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