
Thermo Fisher Scientific TNFR2 Monoclonal Antibody (MR2-1), Biotin
TNFR2 단백질을 인식하는 Biotin 결합 단클론 항체로, WB, IHC(F), Flow Cytometry, Inhibition Assay에 사용 가능. Mouse IgG1 아이소타입이며, 인간 TNFR2 및 원숭이 TNFR2와 교차 반응. 연구용으로 4°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
| Inhibition Assays (IA) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MR2-1 |
| Immunogen | sTNF-R75 purified from the culture supernatant of NSO cells (transfected with the extracellular part of TNF-R75) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Additional Formats
Product Specific Information
This antibody reacts with the extracellular part of TNF-RII and the soluble receptor. It cross-reacts with rhesus and cynomolgus natural TNF-RII.
Target Information
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha and lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2, mediating most metabolic effects of TNF-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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