Thermo Fisher Scientific TK1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 15-194 of human Thymidine Kinase 1 (NP_003249.3). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TK1,uniProtId:P04183-1,ncbiNodeId:9606,antigenRange:15-194,antigenLength:234,antigenImageFileName:PA5-120928_TK1_P04183-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120928_TK1_P04183-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.69 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914500

Product Specific Information

Positive test controls include: HeLa, 293T, Jurkat, Mouse liver, Mouse spleen, Mouse stomach, Rat liver, Rat spleen, Rat stomach. The target is usually found in the following locations: Cytoplasm.

Immunogen sequence: SKTRGQIQVI LGPMFSGKST ELMRRVRRFQ IAQYKCLVIK YAKDTRYSSS FCTHDRNTME ALPACLLRDV AQEALGVAVI GIDEGQFFPD IVEFCEAMAN AGKTVIVAAL DGTFQRKPFG AILNLVPLAE SVVKLTAVCM ECFREAAYTK RLGTEKEVEV IGGADKYHSV CRLCYFKKAS

Target Information

Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5`-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.