Thermo Fisher Scientific PGRMC1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

-

Immunocytochemistry (ICC/IF)

1:50-1:100

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 44-195 of human PGRMC1 (NP_006658.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PGRMC1,uniProtId:O00264-1,ncbiNodeId:9606,antigenRange:44-195,antigenLength:195,antigenImageFileName:PA5-120929_PGRMC1_O00264-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120929_PGRMC1_O00264-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.42 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914501

Product Specific Information

Positive test controls include: HepG2, 293T, SW480, OVCAR3, NCI-H460, Mouse liver, Mouse brain. The target is usually found in the following locations: Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein.

Immunogen sequence: KIVRGDQPAA SGDSDDDEPP PLPRLKRRDF TPAELRRFDG VQDPRILMAI NGKVFDVTKG RKFYGPEGPY GVFAGRDASR GLATFCLDKE ALKDEYDDLS DLTAAQQETL SDWESQFTFK YHHVGKLLKE GEEPTVYSDE EEPKDESARK ND

Target Information

The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.