Thermo Fisher Scientific PGRMC1 Polyclonal Antibody
PGRMC1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 시료에 반응합니다. WB, IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, 고순도 Affinity Chromatography로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 44–195 of human PGRMC1 (NP_006658.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.42 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914501 |
Product Specific Information
Positive test controls include HepG2, 293T, SW480, OVCAR3, NCI-H460, Mouse liver, Mouse brain.
The target is usually found in the following locations: Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein.
Immunogen sequence:
KIVRGDQPAA SGDSDDDEPP PLPRLKRRDF TPAELRRFDG VQDPRILMAI NGKVFDVTKG RKFYGPEGPY GVFAGRDASR GLATFCLDKE ALKDEYDDLS DLTAAQQETL SDWESQFTFK YHHVGKLLKE GEEPTVYSDE EEPKDESARK ND
Target Information
The protein encoded by this gene is a transforming protein related to Rho-specific exchange factors and yeast cell cycle regulators. Expression is elevated with the onset of DNA synthesis and remains high during G2 and M phases. In situ hybridization analysis shows high expression in mitotic cells during liver regeneration, indicating a role in cytokinesis regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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