Thermo Fisher Scientific GABRA2 Monoclonal Antibody (N399/19)

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000
• Publications: View 1 publication

Immunohistochemistry (PFA fixed) (IHC (PFA))

• Tested Dilution: 1:100
• Publications: View publication

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:1,000
• Publications: View publication

Product Specifications

Additional Formats

• APC
• FITC
• PE
• PerCP
• Request custom conjugation

Product Specific Information

• A 1:100 dilution of MA5-27702 was sufficient for detection of GABA-A R, Alpha2 in 20 µg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
• Detects approximately 55 kDa.
• Does not cross-react with GABA-A Receptor Alpha1.
• This antibody was formerly sold as clone S399-19.

Target Information

GABA는 포유류 뇌의 주요 억제성 신경전달물질로, GABA-A 수용체에서 작용하며 이는 리간드 개폐성 염화이온 채널입니다. 벤조디아제핀 등의 약물은 GABA-A 수용체에 결합하여 염화이온 전도성을 조절할 수 있습니다. GABA-A 수용체에는 최소 16개의 서로 다른 서브유닛이 존재하며, 동일한 단백질을 암호화하는 대체 스플라이싱 전사 변이체가 보고되었습니다.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.