Thermo Fisher Scientific EDG1 Monoclonal Antibody (1F11)
EDG1(S1P1) 단백질을 인식하는 Mouse 단클론 항체로 Western blot과 ELISA에 적합. 인간 시료 반응성이 있으며, 액상 형태로 제공. PBS(pH 7.4) 버퍼에 보존제 무첨가, -20°C 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific EDG1 Monoclonal Antibody (1F11)
Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F11 |
| Immunogen | EDG1 (AAH18650, 1 a.a. ~ 47 a.a) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MGPTSVPLVK AHRSSVSDYV NYDIIVRHYN YTGKLNISAD KENSIKL
Target Information
S1P1 is a G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that is coupled to the G(i) subclass of heteromeric G proteins.
S1P1 signaling leads to activation of RAC1, SRC, PTK2/FAK1, and MAP kinases. It plays an important role in cell migration via actin cytoskeleton reorganization and lamellipodia formation in response to sphingosine kinase SPHK1 activity.
S1P1 is required for normal chemotaxis toward sphingosine 1-phosphate, normal embryonic heart development, and cardiac morphogenesis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.