Thermo Fisher Scientific Lamin A/C Recombinant Rabbit Monoclonal Antibody (JE51-60)
Thermo Fisher의 Lamin A/C Recombinant Rabbit Monoclonal Antibody (JE51-60)은 인간 Lamin A/C 단백질을 인식하는 항체로, WB, IHC, ICC, Flow Cytometry에 최적화되어 있습니다. 고순도 단백질 A 정제, 안정적 액상 포맷, 연구용으로 다양한 조직 샘플에 적용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:2000 |
| Immunocytochemistry (ICC/IF) | 1:200 |
| Flow Cytometry (Flow) | 1:1000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE51-60 |
| Immunogen | Recombinant protein within Human Lamin A/C (aa 191–309) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848782 |
Product Specific Information
Positive Control:
A549 cell, A431, SiHa, rat testis tissue, human tonsil tissue, human colon carcinoma tissue, human breast tissue, human gastric carcinoma tissue, mouse brain tissue, Hela.
Target Information
Lamins are intermediate filament proteins forming a network on the inner surface of the nuclear envelope. They exist in three main forms (A, B, and C) and are expressed in various cell types. Lamins A and C are alternatively spliced variants of the LMNA gene.
Mutations in LMNA are associated with multiple disorders, including:
- Emery-Dreifuss muscular dystrophy
- Dunnigan-type familial partial lipodystrophy (FPLD)
- Limb-girdle muscular dystrophy (LGMD1B)
- Dilated cardiomyopathy (CMD1A)
- Axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1)
- Mandibuloacral dysplasia (MAD)
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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