Thermo Fisher Scientific GLB1 Polyclonal Antibody

Thermo Fisher Scientific GLB1 Polyclonal Antibody

Applications and Tested Dilutions

• Western Blot (WB): 1:500–1:3,000
• Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:1,000
• Immunocytochemistry (ICC/IF): Assay-dependent

Product Specifications

Product Specific Information

• Keep as concentrated solution.
• Predicted reactivity: Dog (82%), Cat (81%).
• Positive Control: A431, H1299, HeLa, HepG2.
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Beta Galactosidase encodes a member of the glycosyl hydrolase 35 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme. This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates. Mutations in this gene have been associated with GM1-gangliosidosis and Morquio B syndrome. Diseases associated with GLB1 include GM1-Gangliosidosis Type I and Type II.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.