Thermo Fisher Scientific ALDH7A1 Polyclonal Antibody
ALDH7A1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC에 사용 가능. 인간 및 마우스 반응성 확인. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 완충액에 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human ALDH7A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792334 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (88%), Rat (90%), Zebrafish (84%), Xenopus laevis (84%), Bovine (97%).
- Positive Control: HepG2.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes play a major role in detoxifying aldehydes generated by alcohol metabolism and lipid peroxidation. This member has homology to a previously described protein from the green garden pea (26g pea turgor protein) and is involved in lysine catabolism in the mitochondrial matrix.
Recent studies show localization in both cytosol and mitochondria, likely due to alternative translation initiation sites. An additional variant encoding a different isoform has also been identified. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have been identified.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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