Thermo Fisher Scientific Phospho-S6 (Ser240) Polyclonal Antibody
Phospho-S6 (Ser240) Rabbit Polyclonal Antibody로 인간, 마우스, 랫트 시료에서 S6 단백질의 인산화 형태를 검출. WB, IHC, ICC/IF에 사용 가능. 고순도(>95%) 항체로 항원 친화 크로마토그래피 정제. 연구용으로 단백질 합성 및 세포 성장 조절 연구에 적합.
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Thermo Fisher Scientific Phospho-S6 (Ser240) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human Ribosomal Protein S6 around the phosphorylation site of Serine 240 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553709 |
Product Specific Information
- Detects endogenous protein at a molecular weight of 29 kDa
- Purity >95% by SDS-PAGE
Target Information
Ribosomes are organelles that catalyze protein synthesis, consisting of a small 40S subunit and a large 60S subunit. These subunits are composed of 4 RNA species and approximately 80 distinct proteins. The encoded cytoplasmic ribosomal protein is part of the 40S subunit and belongs to the S6E family. It is a major substrate of ribosomal protein kinases, with phosphorylation occurring on five C-terminal serine residues. Phosphorylation is induced by growth factors, tumor-promoting agents, and mitogens, while dephosphorylation occurs at growth arrest. This protein may regulate cell growth and proliferation through selective translation of specific mRNA classes. Multiple processed pseudogenes of this gene exist throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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