Thermo Fisher Scientific SGK196 Monoclonal Antibody (OTI4F6), TrueMAB

Applications

• Western Blot (WB)
  Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The SGK196 (POMK) gene encodes a protein involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (α-DG), forming transmembrane linkages between the extracellular matrix and the cytoskeleton.
Loss-of-function mutations are associated with Walker-Warburg syndrome (WWS).
In mice, deficiency leads to misplaced neurons (heterotopia) due to defects in neuronal migration.
Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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