Thermo Fisher Scientific SGK196 Monoclonal Antibody (OTI4F6), TrueMAB
SGK196 단백질을 인식하는 Mouse IgG2a 단일클론 항체로 Western blot에 최적화되어 있습니다. 인간 시료 반응성이 있으며, 동결건조 형태로 제공됩니다. 재조합 단백질 기반 면역원으로 제작되어 높은 특이성과 재현성을 제공합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 141–350 of human SGK196 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The SGK196 (POMK) gene encodes a protein involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (α-DG), forming transmembrane linkages between the extracellular matrix and the cytoskeleton.
Loss-of-function mutations are associated with Walker-Warburg syndrome (WWS).
In mice, deficiency leads to misplaced neurons (heterotopia) due to defects in neuronal migration.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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